Objective: The first aim of this study was to determine the prevalence of childhood and current attention deficit hyperactivity disorder (ADHD) symptoms in patients with fibromyalgia. The second aim is to assess the role of depression and anxiety on the relationship between childhood and adult ADHD symptoms with disease impact in this population.

Methods: Sixty-four patients with fibromyalgia were compared to matched 58 healthy controls. All participants completed the Wender Utah Rating Scale (WURS), Adult ADHD Self-Report Scale (ASRS), Beck Depression Inventory (BDI), Beck Anxiety Inventory (BAI) and Fibromyalgia Impact Questionnaire (FIQ).

Results: Patients with fibromyalgia had significantly higher mean scores of depression (BDI), anxiety (BAI), childhood ADHD symptoms (WURS) and adult ADHD symptoms (ASRS total, ASRS hyperactivity/impulsivity subscale and ASRS attention deficit subscale) than the control group. Fibromyalgia impact (FIQ) was significantly correlated with depression (BDI; r = 0.57, p < .001), anxiety (BAI; r = 0.56, p < .001) and childhood ADHD symptoms (WURS; r = 0.41, p < .001) in fibromyalgia group. There was no significant correlation between fibromyalgia impact (FIQ) and adult ADHD symptoms (ASRS total or sub-scale scores). Hierarchical multiple regression indicated that childhood ADHD symptoms (WURS), anxiety (BAI) and depression (BDI) predicted fibromyalgia impact. Both anxiety (BAI) and depression (BDI) mediated the relationship between childhood ADHD symptoms (WURS) and fibromyalgia impact (FIQ).

Conclusion: Childhood ADHD symptoms may be a contributory factor to poorer functioning in the patients with fibromyalgia. The relationship was more pronounced in the presence of depression and anxiety symptoms. Evaluation of childhood and adult ADHD symptoms in patients with fibromyalgia is important for recognition and treatment of ADHD comorbidity and also for attenuating the severity of the disease.

目的：本研究的首要目的是确定纤维肌痛患者的儿童期和当前的注意缺陷多动障碍（ADHD）症状的患病率。第二个目标是评估抑郁症和焦虑症在儿童和成人ADHD症状与疾病影响之间的关系。

方法：将64名纤维肌痛患者与58名健康对照者进行比较。所有参与者均完成了《犹他州温德氏评分量表（WURS），成人ADHD自我报告量表（ASRS），贝克抑郁量表（BDI），贝克焦虑量表（BAI）和纤维肌痛影响问卷（FIQ）。

结果：纤维肌痛患者的抑郁（BDI），焦虑（BAI），儿童ADHD症状（WURS）和成人ADHD症状（ASRS总数，ASRS多动/冲动分量表和ASRS注意缺陷分量表）的平均得分明显高于对照组。纤维肌痛影响（FIQ）与抑郁症（BDI; r  = 0.57，p <.001），焦虑症（BAI; r  = 0.56，p <.001）和儿童ADHD症状（WURS; r  = 0.41，p<.001）在纤维肌痛组中。纤维肌痛影响（FIQ）与成人ADHD症状（ASRS总分或次级量表评分）之间无显着相关性。分层多元回归表明，儿童多动症的症状（WURS），焦虑（BAI）和抑郁（BDI）可预测纤维肌痛的影响。焦虑（BAI）和抑郁（BDI）都介导了儿童ADHD症状（WURS）与纤维肌痛影响（FIQ）之间的关系。

结论：儿童多动症的症状可能是纤维肌痛患者功能较差的一个因素。在出现抑郁和焦虑症状时，这种关系更为明显。对纤维肌痛患者的儿童和成人ADHD症状的评估对于ADHD合并症的识别和治疗以及减轻疾病的严重性很重要。