Background: The greatest burden of sepsis- and septic shock-related morbidity and mortality is in low- and middle-income countries (LMICs). Accurate tracking of incidence and outcomes of patients in LMICs with sepsis has been limited by changing definitions, lack of diagnosis coding and health records, and deficits in personnel. Improving sepsis care in LMICs requires studying outcomes prospectively so that setting appropriate definitions, scoring systems, and treatment guidelines can be created. Our goal is to review the burden of sepsis and septic shock in LMICs, the evolution and applicability of definitions to LMICs, and management.

中文翻译：

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低收入和中等收入国家的败血症和败血性休克。

背景：与败血症和败血性休克相关的发病率和死亡率的最大负担是在中低收入国家（LMIC）。由于定义改变，缺乏诊断编码和健康记录以及人员不足，限制了对患有败血症的中低收入国家患者的发病率和结果的准确追踪。改善中低收入国家的败血症治疗需要前瞻性地研究结果，以便可以制定适当的定义，评分系统和治疗指南。我们的目标是审查LMIC中败血症和败血性休克的负担，定义对LMIC的演变和适用性以及管理。