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Current Progress in Biomedical Applications of Chitosan-Carbon Nanotube Nanocomposites: A Review.
Mini-Reviews in Medicinal Chemistry ( IF 3.3 ) Pub Date : 2020-09-30 , DOI: 10.2174/1389557520666200513120407
Katarzyna Pieklarz 1 , Michał Tylman 1 , Zofia Modrzejewska 1
Affiliation  

The currently observed development of medical science results from the constant search for innovative solutions to improve the health and quality of life of patients. Particular attention is focused on the design of a new generation of materials with a high degree of biocompatibility and tolerance towards the immune system. In addition, apart from biotolerance, it is important to ensure appropriate mechanical and technological properties of materials intended for intra-body applications. Knowledge of the above parameters becomes the basis for considerations related to the possibilities of choosing the appropriate polymer materials. The researchers' interest, as evidenced by the number of available publications, is attracted by nanobiocomposites based on chitosan and carbon nanotubes, which, due to their properties, enable integration with the tissues of the human body. Nanosystems can be used in many areas of medicine. They constitute an excellent base for use as dressing materials, as they exhibit antimicrobial properties. In addition, they can be carriers of drugs and biological macromolecules and can be used in gene therapy, tissue engineering, and construction of biosensors. For this reason, potential application areas of chitosan-carbon nanotube nanocomposites in medical sciences are presented in this publication, considering the characteristics of the system components.



中文翻译:

壳聚糖-碳纳米管纳米复合材料在生物医学应用方面的最新进展:综述。

当前观察到的医学科学发展源于不断寻求创新解决方案以改善患者的健康和生活质量。特别关注的重点是具有高度生物相容性和对免疫系统的耐受性的新一代材料的设计。另外,除了生物耐受性之外,重要的是确保用于体内应用的材料的适当机械和技术性能。上述参数的知识成为考虑与选择合适的聚合物材料的可能性有关的基础。壳聚糖和碳纳米管为基础的纳米生物复合材料吸引了研究人员的兴趣,这一点已经得到了可利用的出版物的证明,由于它们的特性,能够与人体组织整合。纳米系统可用于医学的许多领域。它们构成抗菌材料,因此成为用作敷料的优良基础。此外,它们可以作为药物和生物大分子的载体,并可以用于基因治疗,组织工程和生物传感器的构建。因此,考虑到系统组件的特性,本出版物介绍了壳聚糖-碳纳米管纳米复合材料在医学中的潜在应用领域。它们可以作为药物和生物大分子的载体,并可以用于基因治疗,组织工程和生物传感器的构建。因此,考虑到系统组件的特性,本出版物介绍了壳聚糖-碳纳米管纳米复合材料在医学中的潜在应用领域。它们可以作为药物和生物大分子的载体,并可以用于基因治疗,组织工程和生物传感器的构建。因此,考虑到系统组件的特性,本出版物介绍了壳聚糖-碳纳米管纳米复合材料在医学中的潜在应用领域。

更新日期:2020-11-12
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