White (WAT) and brown (BAT) adipose tissue communicate with skeletal muscle and heart through the secretion of adipokines (adiponectin, leptin, omentin, osteopontin or cardiotrophin-1) and batokines (BMP8b, FGF-21, endothelin-1 or IL-6), respectively. Furthermore, several bioactive lipids termed lipokines [palmitoleate (C16:1n7) or 12,13-diHOME] and microRNAs capsuled in exosomes (miR-27a, miR122, miR-130b, miR-155, miR-200a or miR-320d) secreted from white and brown adipocytes also influence the skeletal and cardiac muscle function. The review focuses on the depot-related differences in adipose tissue-derived signals (adipokines, batokines, lipokines and exosomal miRNAs) and their impact on skeletal muscle under physiological conditions as well as in obesity. The relevance of regular physical activity and exercise on fat depot-specific adaptations to improve metabolic health will also be addressed.

中文翻译：

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脂肪因子中脂肪组织库的差异以及对骨骼肌和心肌的影响。

白色 (WAT) 和棕色 (BAT) 脂肪组织通过分泌脂肪因子（脂联素、瘦素、网膜蛋白、骨桥蛋白或心肌营养素-1）和脂肪因子（BMP8b、FGF-21、内皮素-1 或 IL- 6) 分别。此外，被称为脂因子 [棕榈油酸酯 (C16:1n7) 或 12,13-diHOME] 的几种生物活性脂质和包裹在外泌体中的微 RNA（miR-27a、miR122、miR-130b、miR-155、miR-200a 或 miR-320d）分泌来自白色和棕色脂肪细胞的脂肪也会影响骨骼肌和心肌功能。该综述重点关注脂肪组织衍生信号（脂肪因子、batokines、脂质因子和外泌体 miRNA）的库相关差异及其在生理条件下和肥胖时对骨骼肌的影响。