Association of AMPK Pathway-Related Gene Polymorphisms with Symptomatic Intracranial Atherosclerotic Stenosis in a Chinese Han Population.,Genetic Testing and Molecular Biomarkers

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Association of AMPK Pathway-Related Gene Polymorphisms with Symptomatic Intracranial Atherosclerotic Stenosis in a Chinese Han Population.
Genetic Testing and Molecular Biomarkers ( IF 1.1 ) Pub Date : 2020-05-07 , DOI: 10.1089/gtmb.2019.0227
Zeyu Liu ₁ , Xiaoqing Zhou ₁ , Junyan Wang ₁ , Fang Yu ₁ , Xianjing Feng ₁ , Qin Huang ₁ , Di Liao ₁ , Xi Li ₁ , Qiong Zhan ₂ , Yunhai Liu ₁ , Qidong Yang ₁ , Xin Jin ₃ , Jian Xia _{1,

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Affiliation

Background and Objective: Recently, AMP-activated protein kinase (AMPK) signaling was confirmed to be intimately associated with atherosclerosis. Evidence indicates that genetic susceptibility plays an important role in the etiology of symptomatic intracranial atherosclerotic stenosis (sICAS), however few genes have been pinpointed being etiologically associated. This study investigated possible links between single nucleotide polymorphisms (SNPs) of AMPK-related genes and sICAS in Han Chinese subjects.

更新日期：2020-05-07

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