Introduction

Laboratory comments appended on clinical biochemistry reports are common in the UK. Although popular with clinicians and the public, there is little evidence that these comments influence the clinical management of patients.

Methods

We provided reflex automated laboratory comments on all primary care lipid results including, if appropriate, recommendation of direct referral to the West Midlands Familial Hypercholesterolaemia service (WMFHS). Over a two-year period, the number GP referrals from the Wolverhampton City Clinical Commissioning Group (CCG) to the WMFHS were compared with four comparator CCGs of similar population size, who were not provided with reflex laboratory comments.

Results

Over the study period, the WMFHS received more referrals from Wolverhampton GPs (241) than any other comparator CCG (range 8–65) and greater than the combined referrals (172) from all four comparator CCGs.

Conclusion

Targeted reflex laboratory comments may influence the clinical management of patients and may have a role in the identification of individuals with familial hypercholesterolaemia.

中文翻译：

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对实验室报告的反思评论会改变患者管理吗？

介绍

附在临床生化报告上的实验室评论在英国很普遍。尽管在临床医生和公众中很流行，但很少有证据表明这些评论影响患者的临床管理。

方法

我们对所有初级保健脂质结果均提供了自动反射实验室评论，包括在适当情况下建议直接转诊至西米德兰兹家族性高胆固醇血症服务（WMFHS）。在两年的时间里，将伍尔弗汉普顿市临床调试小组（CCG）推荐给WMFHS的GP推荐人数与四个相似人口规模的比较CCG进行了比较，但没有提供反射实验室评论。

结果

在研究期间，WMFHS从Wolverhampton GP收到的转介数（241）比其他任何比较者CCG（8-65）都多，并且从所有四个比较者CCG的转介（172）都多。

结论

有针对性的反射实验室意见可能会影响患者的临床管理，并且可能在鉴定家族性高胆固醇血症患者中发挥作用。