Abstract

An eco-safe synthetic route for convenient one-pot synthesizing 1H-pyrazolo[1,2-b] phthalazine-5,10-dione derivatives through Knoevenagel-Michael cyclocondensation is reported in carboxymethyl cellulose (CMC) based on green chemistry principles. The prominent benefits include use of recyclable green catalyst, commercially accessible inexpensive starting materials, operational simplicity, non-hazardous reaction circumstances, high atom-economy, solvent-free, short reaction times and high yields.

中文翻译：

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羧甲基纤维素 (CMC) 作为可回收绿色催化剂促进 1H-吡唑并[1,2-b]酞嗪-5,10-二酮衍生物无溶剂合成的环保协议

摘要

基于绿色化学原理，在羧甲基纤维素（CMC）中报道了一种生态安全的合成路线，可通过Knoevenagel-Michael 环缩合一锅法方便地合成 1 H-吡唑并[1,2 - b ] 酞嗪-5,10-二酮衍生物。突出的好处包括使用可回收的绿色催化剂、商业上可获得的廉价起始材料、操作简单、无危险的反应环境、高原子经济性、无溶剂、反应时间短和产率高。