Topical application is an important administration route for drugs requiring local action on the skin, thereby avoiding their systemic absorption and adverse side effects. Rosmarinus officinalis L. (syn. Salvia rosmarinus Spenn.), popularly known as rosemary, is an aromatic plant with needle-like leaves belonging to the Lamiaceae family. Rosemary has therapeutic properties and has been used in the folk medicine, pharmaceutical, and cosmetics industries, mainly for its antioxidant and anti-inflammatory properties, which are attributed to the presence of carnosol/carnosic and ursolic acids. The therapeutic use of rosemary has been explored for the treatment of inflammatory diseases; however, other uses have been studied, such as wound healing and skin cancer and mycoses treatments, among others. Besides it therapeutic uses, rosemary has potential applications in cosmetic formulations and in the treatment of pathological and non-pathological conditions, such as cellulite, alopecia, ultraviolet damage, and aging. This review aims to critically discuss the topical applications of rosemary found in the literature while also offering relevant information for the development of topical formulations of its bioactive compounds.

中文翻译：

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迷迭香（Rosmarinus officinalis L.，syn Salvia rosmarinus Spenn。）及其局部应用：综述。

对于需要在皮肤上局部作用的药物，局部施用是重要的给药途径，从而避免了其全身吸收和不良副作用。迷迭香（Rosmarinus officinalis L.（Salvia rosmarinus Spenn。）的统称，迷迭香）是一种芳香植物，带有针状叶，属于唇形科家庭。迷迭香具有治疗性能，并且已在民间医学，制药和化妆品行业中使用，主要是由于其抗氧化剂和抗炎特性，这归因于鼠尾草酚/肌酸和熊果酸的存在。已经探索了迷迭香在炎性疾病中的治疗用途。然而，还研究了其他用途，例如伤口愈合，皮肤癌和真菌病治疗。迷迭香除具有治疗用途外，还具有潜在的用途，可用于化妆品配方以及病理性和非病理性疾病的治疗，例如脂肪团，脱发，紫外线损伤和衰老。