Biofilms are clusters of bacteria that live in association with surfaces. Their main characteristic is that the bacteria inside the biofilms are attached to other bacterial cells and to the surface by an extracellular polymeric matrix. Biofilms are capable of adhering to a wide variety of surfaces, both biotic and abiotic, including human tissues, medical devices, and other materials. On these surfaces, biofilms represent a major threat causing infectious diseases and economic losses. In addition, current antibiotics and common disinfectants have shown limited ability to remove biofilms adequately, and phage-based treatments are proposed as promising alternatives for biofilm eradication. This review analyzes the main advantages and challenges that phages can offer for the elimination of biofilms, as well as the most important factors to be taken into account in order to design effective phage-based treatments.

中文翻译：

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去除生物膜的噬菌体。

生物膜是与表面结合生活的细菌簇。它们的主要特征是生物膜内部的细菌通过细胞外聚合物基质附着到其他细菌细胞和表面。生物膜能够粘附在生物和非生物的多种表面上，包括人体组织，医疗设备和其他材料。在这些表面上，生物膜是造成传染病和经济损失的主要威胁。另外，目前的抗生素和普通消毒剂显示出充分去除生物膜的能力有限，并且提出了基于噬菌体的疗法作为根除生物膜的有希望的替代方法。这篇评论分析了噬菌体可以消除生物膜的主要优势和挑战，