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Hypoxia-responsive miR-141-3p is involved in the progression of breast cancer via mediating the HMGB1/HIF-1α signaling pathway.
The Journal of Gene Medicine ( IF 3.2 ) Pub Date : 2020-05-21 , DOI: 10.1002/jgm.3230
Shanping Sun 1, 2 , Jinglin Ma 2 , Panpan Xie 2 , Zhen Wu 2 , Xingsong Tian 3
Affiliation  

Hypoxia‐responsive miRs have been frequently reported in the growth of various malignant tumors. The present study aimed to investigate whether hypoxia‐responsive miR‐141–3p was implicated in the pathogenesis of breast cancer via mediating the high‐mobility group box protein 1 (HMGB1)/hypoxia‐inducible factor (HIF)‐1α signaling pathway.

中文翻译:

缺氧反应性 miR-141-3p 通过介导 HMGB1/HIF-1α 信号通路参与乳腺癌的进展。

缺氧反应性 miRs 在各种恶性肿瘤的生长中经常被报道。本研究旨在通过介导高迁移率组盒蛋白 1 (HMGB1)/缺氧诱导因子 (HIF)-1α 信号通路,探讨缺氧反应性 miR-141-3p 是否与乳腺癌的发病机制有关。
更新日期:2020-05-21
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