Indeterminate thyroid nodules in the era of molecular genomics.,Molecular Genetics & Genomic Medicine

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Indeterminate thyroid nodules in the era of molecular genomics.
Molecular Genetics & Genomic Medicine ( IF 1.5 ) Pub Date : 2020-05-21 , DOI: 10.1002/mgg3.1288
Sarika N Rao ₁ , Victor Bernet ₁

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Indeterminate thyroid nodules are diagnosed in up to 30% of fine‐needle aspirations and the risk of malignancy in these cases are highly variable. Consequently, managing these nodules has been a challenge. While a diagnostic thyroidectomy would help clarify the pathology, there is the risk of developing surgical‐related complications for a procedure that may not have been necessary and associated high costs. Genomic testing of indeterminate thyroid nodules may help better guide management.

中文翻译：

分子基因组学时代的不确定甲状腺结节。

高达30％的细针穿刺误诊为不确定的甲状腺结节，在这些情况下，发生恶性肿瘤的风险差异很大。因此，管理这些结节一直是一个挑战。虽然诊断性甲状腺切除术有助于明确病理，但存在手术相关并发症的风险，因为该手术可能不必要，且成本较高。对不确定的甲状腺结节进行基因组测试可能有助于更好地指导治疗。

更新日期：2020-05-21

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