Magnetic resonance‐guided radiation therapy (MRgRT) has shown great promise for localization and real‐time tumor monitoring. However, to date, quantitative imaging has been limited for low field MRgRT. This work benchmarks quantitative T1, R2*, and Proton Density (PD)mapping in a phantom on a 0.35 T MR‐linac and implements a novel acquisition method, STrategically Acquired Gradient Echo (STAGE). To further validate STAGE in a clinical setting, a pilot study was undertaken in a cohort of brain tumor patients to elucidate opportunities for longitudinal functional imaging with an MR‐linac in the brain.

中文翻译：

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在 0.35T MR-linac 上进行快速多对比脑成像。

磁共振引导放射治疗 (MRgRT) 在定位和实时肿瘤监测方面显示出巨大的前景。然而，迄今为止，低场 MRgRT 的定量成像受到限制。这项工作基准测试定量T1，R2 *，和质子密度（PD）映射在一个0.35 T先生-直线加速器和工具的新颖采集方法中的幻象，ST rategically甲cquired ģ radient ë町（STAGE）。为了在临床环境中进一步验证 STAGE，在一组脑肿瘤患者中进行了一项初步研究，以阐明在大脑中使用 MR-linac 进行纵向功能成像的机会。