当前位置: X-MOL 学术Trends Biochem. Sci. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Managing Hyperosmotic Stress through Phase Separation.
Trends in Biochemical Sciences ( IF 13.8 ) Pub Date : 2020-05-21 , DOI: 10.1016/j.tibs.2020.05.004
Ivan Peran 1 , Nafiseh Sabri 1 , Tanja Mittag 1
Affiliation  

In a recent study, Yasuda et al. show how liquid–liquid phase separation (LLPS) under hyperosmotic stress conditions allows cells to react to ubiquitinated proteins and to assemble nuclear, liquid compartments that recruit proteasomes and result in aggregate clearance.



中文翻译:

通过相分离管理高渗压力。

Yasuda等人在最近的一项研究中展示了在高渗胁迫条件下的液相-液相分离(LLPS)如何使细胞与泛素化的蛋白质发生反应,并组装可吸收蛋白酶体并导致聚集物清除的核液室。

更新日期:2020-05-21
down
wechat
bug