Membrane applications are hindered by fouling. Photoactive membranes (containing photosensitizers) show photodynamic antimicrobial chemotherapy (PACT) activity which reduces biological fouling. In this work we use phthalocyanines (Pcs) as photosensitizers. The Pcs used are: 2-(4-carboxyphenoxy)-9(10), 16(17), 23(24)-tris(dimethylamino) phthalocyaninato zinc(II) (1) and the quaternized 2-(4-carboxyphenoxy)-9(10), 16(17), 23(24)-tris(trimethylamino) phthalocyanine zinc(II) methyl sulfate (2). Complex 2 showed an enhanced singlet oxygen quantum yield (Φ_Δ) of 0.76 compared to 0.53 for 1. Complex 2 showed enhanced PACT activity against Staphylococcus aureus giving a log reduction value of 9.4, while its precursor (complex 1) gave 0.08. The complexes were then conjugated to amine-functionalized polystyrene and embedded into polystyrene to form membranes resulting in Φ_Δ values of 0.24 and 0.27 for complexes 1 and 2 respectively in water. The latter membrane showed better PACT activity.

结垢会阻碍膜的应用。光敏膜（包含光敏剂）显示出光动力学抗微生物化学疗法（PACT）活性，可减少生物污染。在这项工作中，我们使用酞菁（Pcs）作为光敏剂。使用的Pcs为：2-（4-羧基苯氧基）-9（10），16（17），23（24）-三（二甲基氨基）酞菁锌（II）（1）和季铵化的2-（4-羧基苯氧基） -9（10），16（17），23（24）-三（三甲基氨基）酞菁硫酸锌锌（II）（2）。复杂2显示出增强的单线态氧量子产率（Φ _Δ为0.76）相比，0.53 1。复合物2对金黄色葡萄球菌显示增强的PACT活性给出的对数减少值为9.4，而其前体（配合物1）的减少值为0.08。然后将络合物与胺官能化的聚苯乙烯偶联，并包埋在聚苯乙烯中以形成膜，从而使水中的络合物1和2的_ΦΔ值分别为0.24和0.27 。后者的膜显示出更好的PACT活性。