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Tanner's tempo of growth in adolescence: recent SITAR insights with the Harpenden Growth Study and ALSPAC.
Annals of Human Biology ( IF 1.2 ) Pub Date : 2020-03-01 , DOI: 10.1080/03014460.2020.1717615
T J Cole 1
Affiliation  

Background: James Tanner emphasised the "tempo" of growth, i.e. the adolescent spurt as summarised by its timing (age at peak velocity or APV) and intensity (peak velocity, PV).Aim: The paper applies the SITAR growth curve model to pubertal growth data with the aim of clarifying the growth pattern across multiple measurements and the spectrum of APV and PV.Subjects and methods: Data for 7-20 years on ten anthropometric measurements in 619 children from the Harpenden Growth Study, and on height in 10410 children from the ALSPAC study, were analysed using SITAR (SuperImposition by Translation And Rotation). SITAR models pubertal growth as a mean curve with APV and PV fitted as subject-specific random effects, and a random measurement intercept.Results: Mean APV for Harpenden girls and boys averaged 12.0 and 13.9 years across the ten measurements. PV expressed as percent per year lay in the narrow range 4-8%. Splitting the ALSPAC subjects into 9 by 5 APV and PV groups and fitting separate SITAR models to each group confirmed SITAR's good fit while highlighting the spectrum of growth patterns.Conclusion: SITAR works well to summarise pubertal growth. The disappointment is that Tanner did not live to see it in action.

中文翻译:

Tanner 在青春期的成长速度:Harpenden Growth Study 和 ALSPAC 最近对 SITAR 的见解。

背景:James Tanner 强调了生长的“节奏”,即青春期的突增,通过时间(峰值速度或 APV)和强度(峰值速度,PV)来概括。目的:本文将 SITAR 生长曲线模型应用于青春期生长数据,旨在阐明跨越多个测量值的生长模式以及 APV 和 PV 的光谱。主题和方法:来自 Harpenden 生长研究的 619 名儿童的 10 次人体测量数据,以及 10410 名儿童的身高数据,为期 7-20 年来自 ALSPAC 研究,使用 SITAR(平移和旋转叠加拼版)进行了分析。SITAR 将青春期生长建模为一条平均曲线,其中 APV 和 PV 拟合为特定于受试者的随机效应,以及随机测量截距。结果:Harpenden 女孩和男孩的平均 APV 为 12.0 和 13。9年跨越十次测量。以每年百分比表示的 PV 处于 4-8% 的狭窄范围内。将 ALSPAC 受试者分成 9 x 5 个 APV 和 PV 组,并为每个组拟合单独的 SITAR 模型,这证实了 SITAR 的良好拟合,同时突出了生长模式的范围。结论:SITAR 很好地总结了青春期的生长。令人失望的是坦纳没有活着看到它在行动。
更新日期:2020-05-20
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