Canine hip dysplasia is characterized by poor hip joint conformation and laxity. The disease is a complex trait influenced by both genetics and environment. Diagnosis and quantification of hip dysplasia are performed by radiographic examination of the hip joint and the diagnosis is used for making breeding decisions in many breeds. A prognostic genetic test (the Dysgen test) based on seven associated SNPs has been developed in a study based on Spanish Labrador Retrievers. In our study this test has been evaluated in 39 Danish Labrador Retrievers with known radiographic hip score: 14 with hip dysplasia (grade D or E) and 25 without hip dysplasia (grade A or B). There was no significant correlation between the Dysgen test results and the radiographic hip status (P  = 0.3203) in these dogs, indicating that Dysgen test results obtained for Danish Labrador Retrievers have no prognostic value.

中文翻译：

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丹麦拉布拉多犬的髋关节发育不良的DNA测试验证失败。

犬髋关节发育不良的特征是髋关节构象差和松弛。该病是受遗传和环境影响的复杂特征。髋关节发育异常的诊断和定量通过影像学检查髋关节进行，该诊断可用于做出许多品种的育种决策。在基于西班牙拉布拉多犬的一项研究中，开发了基于七个相关SNP的预后基因测试（Dysgen测试）。在我们的研究中，已对39例已知放射照相髋关节评分的丹麦拉布拉多犬进行了该测试的评估：14例患有髋关节发育不良（D或E级）和25例没有髋关节发育不良（A或B级）。Dysgen测试结果与影像学髋关节状态之间无显着相关性（P = 0.3203）在这些狗中，表明丹麦拉布拉多犬获得的Dysgen测试结果没有预后价值。