Children with SCT have an increased risk of suboptimal neurodevelopment. Previous studies have shown an elevated risk for neurobehavioral problems in individuals with SCT. However, not much is known about neurobehavioral problems in very young children; knowledge that could help with early identification of children at risk for suboptimal development, and that could help establish targets for early intervention. This study addressed the question of what the behavioral profile of children with SCT aged 1–5 years looks like. In total, 182 children aged 1–5 years participated in this study (N_SCT=87, N_{nonclinical controls} = 95). Recruitment and assessment took place in the Netherlands and the United States. The SCT group was recruited through prospective follow‐up (50%), information seeking parents (31%), and clinical referral (18%). Behavioral profiles were assessed with the child behavior checklist and the ages‐and‐stages social–emotional questionnaire.

中文翻译：

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1-5岁儿童性染色体三体性（47，XXX，47，XXY，47，XYY）的行为特征。

SCT患儿神经发育欠佳的风险增加。先前的研究表明，SCT患者出现神经行为问题的风险较高。但是，对于非常年幼的儿童的神经行为问题知之甚少。有助于早期识别处于次优发育风险中的儿童的知识，并有助于建立早期干预的目标。这项研究解决了1至5岁SCT儿童的行为特征如何的问题。共有182名1至5岁的儿童参加了这项研究（N _SCT = 87，N个_{非临床对照）}= 95）。招聘和评估在荷兰和美国进行。通过前瞻性随访（50％），寻求父母的信息（31％）和临床转诊（18％）招募了SCT组。用儿童行为清单和年龄和阶段的社会情感调查表评估行为概况。