Skin plays a significant role in human body function and its collagen states change during the human skin ageing process, which affects skin function. We previously reported on geometry-dependent spectroscopic contrast achieved by spectroscopic micro-optical coherence tomography (SμOCT), which discovered that transversely oriented and regularly arranged nano-cylinders selectively backscatter the long-wavelength lights and generate spectral centroid (SC) shifts towards the long wavelengths within a spectral window of 700 - 950 nm. Here we further proposed a novel method towards indicating the state of human skin in vivo using geometry-dependent spectroscopic contrast imaging. The proposed method can obtain spectroscopic contrast images of different human skin layers, including the papillary dermis and reticular dermis, and provide a quantitative method towards indicating collagen state in human skin in vivo. Experimental results have shown that the proposed method may potentially have the ability to assess the state of human skin.

中文翻译：

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使用几何相关光谱对比成像指示体内人体皮肤状态


皮肤对人体功能起着重要作用，在人体皮肤老化过程中，其胶原蛋白状态发生变化，影响皮肤功能。我们之前报道了通过光谱微光学相干断层扫描（SμOCT）实现的几何依赖的光谱对比度，该研究发现横向定向且规则排列的纳米圆柱体选择性地反向散射长波长光并产生向长波长方向的光谱质心（SC）偏移。 700 - 950 nm 光谱窗口内的波长。在这里，我们进一步提出了一种使用几何依赖的光谱对比成像来指示体内人体皮肤状态的新方法。该方法可以获得不同人体皮肤层（包括乳头真皮和网状真皮）的光谱对比图像，并为指示人体皮肤体内胶原蛋白状态提供定量方法。实验结果表明，所提出的方法可能具有评估人体皮肤状态的能力。