Skin plays a significant role in human body function and its collagen states change during the human skin ageing process, which affects skin function. We previously reported on geometry-dependent spectroscopic contrast achieved by spectroscopic micro-optical coherence tomography ( $\text{S}\mu $ OCT), which discovered that transversely oriented and regularly arranged nano-cylinders selectively backscatter the long-wavelength lights and generate spectral centroid (SC) shifts towards the long wavelengths within a spectral window of $700\;-\;950\;nm$ . Here we further proposed a novel method towards indicating the state of human skin in vivo using geometry-dependent spectroscopic contrast imaging. The proposed method can obtain spectroscopic contrast images of different human skin layers, including the papillary dermis and reticular dermis, and provide a quantitative method towards indicating collagen state in human skin in vivo. Experimental results have shown that the proposed method may potentially have the ability to assess the state of human skin.

中文翻译：

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使用几何相关的光谱对比成像在体内指示人体皮肤状态

皮肤在人体机能中起着重要作用，其胶原蛋白状态在人体皮肤老化过程中发生变化，从而影响皮肤功能。我们之前报道了通过光谱微光学相干断层扫描实现的几何相关光谱对比度。 $\text{S}\mu $ OCT），他们发现横向定向和规则排列的纳米圆柱选择性地反向散射长波长光并产生光谱质心（SC）在光谱窗口内向长波长移动 $700\;-\;950\;nm$ . 在这里，我们进一步提出了一种使用几何相关光谱对比成像指示体内人体皮肤状态的新方法。该方法可以获得不同人体皮肤层的光谱对比图像，包括乳头状真皮和网状真皮，并提供了一种在体内指示人体皮肤胶原状态的定量方法。实验结果表明，所提出的方法可能具有评估人体皮肤状态的潜力。