Highly efficient enrichment of N-glycopeptides by two-dimensional Hf-based metal-organic framework nanosheets.,Analyst

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Highly efficient enrichment of N-glycopeptides by two-dimensional Hf-based metal-organic framework nanosheets.
Analyst ( IF 3.6 ) Pub Date : 2020-05-19 , DOI: 10.1039/d0an00647e
Shi-Shu Yang ₁ , Chen Wang , Jing Xiao , Xizhong Yu , Wenbin Shang , David Da Yong Chen , Zhi-Yuan Gu

Affiliation

Highly efficient enrichment of target glycopeptides plays a crucial role in glycoproteome research. Owing to their large surface area and excellent hydrophilicity, 2-D Hf-BTB nanosheets showed effective and selective enrichment of 78 glycopeptides derived from 29 glycoproteins with 90 N-glycosylation sites from just 2 μL of human serum.

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