A wealth of rapidly evolving reports suggests that olfaction and taste disturbances may be manifestations of the novel COVID-19 pandemic. While otolaryngological societies worldwide have started to consider chemosensory evaluation as a screening tool for COVID-19 infection, the true nature of the relationship between the changes in chemosensory ability and COVID-19 is unclear. Our goal with this review is to provide a brief overview of published and archived literature, as well as the anecdotal reports and social trends related to this topic up to April 29, 2020. We also aim to draw parallels between the clinical/chemosensory symptomology reported in association to past coronavirus pandemics (such as SARS and MERS) and the novel COVID-19. This review also highlights current evidence on persistent chemosensory disturbances after the infection has resolved. Overall, our analysis pinpoints the need for further studies: (1) to better quantify olfaction and taste disturbances associated with SARS-CoV-2 infection, compared to those of other viral and respiratory infections, (2) to understand the relation between smell, taste, and chemesthesis disturbances in COVID-19, and (3) to understand how persistent are these disturbances after the infection has resolved.

中文翻译：

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电晕病毒和化学感官：过去、现在和未来。


大量迅速发展的报告表明，嗅觉和味觉障碍可能是新型冠状病毒肺炎 (COVID-19) 大流行的表现。虽然世界各地的耳鼻喉科学会已开始考虑将化学感应评估作为 COVID-19 感染的筛查工具，但化学感应能力的变化与 COVID-19 之间关系的真正性质尚不清楚。我们这篇综述的目标是提供截至 2020 年 4 月 29 日已发表和存档的文献的简要概述，以及与该主题相关的轶事报告和社会趋势。我们还旨在在报告的临床/化学感觉症状学之间进行比较与过去的冠状病毒大流行（例如 SARS 和 MERS）和新型 COVID-19 相关。这篇综述还强调了感染消退后持续化学感觉紊乱的当前证据。总体而言，我们的分析指出需要进一步研究：(1) 与其他病毒和呼吸道感染相比，更好地量化与 SARS-CoV-2 感染相关的嗅觉和味觉障碍，(2) 了解气味之间的关系， (3) 了解感染消退后这些紊乱的持续程度。