Abstract Chitosan was synthesized from chitin; extracted from prawn shells’ powder via deacetylation and physicochemical properties were studied. Novel chitosan derivatives of 2-imidazolecarboxaldehyde and 2-thiophenecarboxaldehyde were synthesized by refluxing equimolar quantities of respective aldehyde with chitosan. These functionalized chitosan derivatives were characterized by Fourier transform infrared (FTIR), 13C-nuclear magnetic resonance (13C-NMR) spectroscopy, elemental analysis, X-ray diffraction (XRD), thermogravimetric analysis (TGA) and differential thermal analysis (DTA) and their antibacterial activity was explored. Chitosan derivative of 2-thiophenecarboxaldehyde was found active against Escherichia coli. GRAPHICAL ABSTRACT

中文翻译：

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2-咪唑甲醛和2-噻吩甲醛的新型壳聚糖衍生物及其抗菌活性

摘要 壳聚糖是以甲壳素为原料合成的；研究了从虾壳粉中脱乙酰化提取的产物及其理化性质。2-咪唑甲醛和2-噻吩甲醛的新型壳聚糖衍生物通过将等摩尔量的相应醛与壳聚糖回流合成。这些功能化的壳聚糖衍生物通过傅里叶变换红外 (FTIR)、13C-核磁共振 (13C-NMR) 光谱、元素分析、X 射线衍射 (XRD)、热重分析 (TGA) 和差热分析 (DTA) 进行表征，并且研究了它们的抗菌活性。发现 2-噻吩甲醛的壳聚糖衍生物对大肠杆菌具有活性。图形概要