The purpose of this review is to summarize current knowledge acquired on preclinical (incision, excision, and dead space wound models) and clinical studies regarding topically used herbal products with wound healing activity. The antimicrobial, anti-inflammatory, and antioxidant mechanisms of their action as well as the adverse effects of herbal therapy will be described. Numerous preclinical and few clinical trials have confirmed the activity of herbal products in the stimulation of wound healing. In contrast to synthetic drugs, for which chemical compositions, purity, efficacy, minimal active concentration, and toxicity are well specified, several herbal formulations require further investigations. Nevertheless, it cannot be precluded that herbal products may be considered as an important support during conventional wound healing therapy or even as synthetic medicament replacements.

中文翻译：

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用于术后伤口愈合的草药产品——切口、切除和死腔伤口模型

本综述的目的是总结目前在临床前（切口、切除和死腔伤口模型）和临床研究中获得的关于局部使用的具有伤口愈合活性的草药产品的知识。将描述其作用的抗菌、抗炎和抗氧化机制以及草药疗法的副作用。许多临床前和少数临床试验证实了草药产品在刺激伤口愈合方面的活性。与合成药物相比，合成药物的化学成分、纯度、功效、最小活性浓度和毒性都有明确规定，几种草药配方需要进一步研究。尽管如此，