Little is known about pseudoprogression in brain tumours other than gliomas. A 9-year-old male child with a pineal teratoma/germinoma underwent surgical resection followed by adjuvant chemo-radiotherapy. The magnetic resonance imaging scan 4 months post-radiotherapy showed a contrast-enhancing lesion within the surgical cavity suspicious of recurrence. These radiological findings subsequently resolved without any specific intervention. The child continues in remission 2 years post-treatment. This case illustrates the occurrence of pseudoprogression post-radiotherapy in intracranial GCT and highlights an unmet need for greater implementation of functional imaging techniques in paediatric neuro-oncology to avoid undue discontinuation of effective treatments or inappropriate enrolment in clinical trials.

中文翻译：

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松果生殖细胞瘤患儿放射治疗后的放射学伪进展。

除神经胶质瘤外，关于脑肿瘤的假性进展知之甚少。一名患有松果体畸胎瘤/生殖器瘤的9岁男孩接受了外科手术切除，然后进行了辅助化学放疗。放疗后4个月的磁共振成像扫描显示，手术腔内病变增强，可疑复发。这些放射学发现随后得到解决，无需任何特殊干预。儿童在治疗后2年继续缓解。该病例说明了颅内GCT放射治疗后假性进展的发生，并突显了在小儿神经肿瘤学中对功能成像技术的更大实施的未满足需求，以避免有效治疗的不当终止或临床试验中的不适当入组。