For the first time in this study, curcumin was utilized as an organic component reacting with Cu (II) ion (Cu²⁺) as an inorganic component for fabrication of curcumin based Cu hybrid nanostructure (Cu-hNs). We also systematically examined the catalytic effect towards guaiacol and antimicrobial activities of Cu-hNs towards fish pathogen bacteria. For the characterization of Cu-hNs, Scanning Electron Microscopy (SEM), Energy Dispersive X-ray spectroscopy (EDX) and Fourier transform infrared spectrometry (FT-IR) analysis were used. We claimed that hydroxyl group might react with Cu²⁺ in phosphate solution (PO₄^-3) to form Cu-hNs. However, more uniform and spherical Cu-hNs were not seen owing to absence of more reactive functional groups like amine and carboxyl groups on structure of curcumin. In addition to our findings, synthesis of Cu-hNs were carried out in the various pH values to evaluate the effect of pHs on formation of Cu-hNs. The Cu-hNs exhibited remarkable catalytic activity throught the Fenton reaction in the presence of hydrogen peroxide (H₂O₂) and effective antimicrobial activities against Gram-positive/negative fish pathogen bacteria. In this study, cheap and efficient synthesis of nanoflowers (NFs) using plant extracts is proposed for biomedical applications rather than expensive molecules such as amino acids and DNA.

本研究首次利用姜黄素作为有机成分与作为无机成分的铜(II)离子(Cu ²⁺ )反应来制备姜黄素基铜杂化纳米结构(Cu-hNs)。我们还系统地研究了愈创木酚的催化作用以及 Cu-hNs 对鱼类病原菌的抗菌活性。为了表征 Cu-hNs，使用了扫描电子显微镜 (SEM)、能量色散 X 射线光谱 (EDX) 和傅里叶变换红外光谱 (FT-IR) 分析。我们声称羟基可能与磷酸盐溶液(PO ₄ ^-3 )中的Cu ²⁺反应形成Cu-hNs。然而，由于姜黄素结构上缺乏胺和羧基等更具反应性的官能团，因此没有看到更均匀和球形的 Cu-hN。除了我们的发现之外，还在不同的 pH 值下进行了 Cu-hN 的合成，以评估 pH 对 Cu-hN 形成的影响。 Cu-hNs 在过氧化氢 (H ₂ O ₂ ) 存在下通过芬顿反应表现出显着的催化活性，并对革兰氏阳性/阴性鱼类病原体细菌具有有效的抗菌活性。在这项研究中，建议使用植物提取物廉价而高效地合成纳米花（NF）用于生物医学应用，而不是昂贵的分子（例如氨基酸和DNA）。