Objective

The aim of the present study was to compare localization of the language cortex using electrical cortical stimulation (ECS) and functional magnetic resonance imaging (fMRI) to establish the relevance of fMRI language mapping.

Methods

Language mapping with fMRI and functional ECS mapping were retrospectively compared in ten patients with refractory epilepsy who underwent fMRI language mapping and functional ECS mapping between June 2012 and April 2019. A shiritori task, a popular Japanese word chain game, was used for fMRI language mapping.

Results

BOLD signal activation was observed in the left inferior frontal gyrus (including the pars opecularis and the pars triangularis), and superior temporal gyrus, which is a language-related area, as well as in the left superior and middle frontal gyri, the intraparietal sulcus, and fusiform gyrus. These results were compared with ECS to elucidate the functional role of the activated areas during fMRI language tasks. These activated areas included language areas, negative motor areas, supplementary motor areas (SMAs), and non-functional areas.

Conclusion

The activated areas of fMRI language mapping include language-related areas, the negative motor area, and SMAs. These findings suggest the involvement of language and higher order motor networks in verbal expression.

中文翻译：

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功能性MRI语言映射的解剖和功能分布。

目的

本研究的目的是比较使用电皮层刺激（ECS）和功能磁共振成像（fMRI）对语言皮层的定位，以建立fMRI语言映射的相关性。

方法

回顾性地比较了2012年6月至2019年4月间接受fMRI语言映射和功能ECS映射的10例难治性癫痫患者的功能性磁共振成像和功能性ECS映射。日本流行的单词链游戏shiritori任务用于功能性磁共振成像语言映射。

结果

在与语言相关的区域，左下额叶回（包括视神经睑和三角肌）和颞上回（与语言有关的区域）以及左上额中回和顶额中回（顶内沟）中观察到BOLD信号激活。和梭状回。将这些结果与ECS进行比较，以阐明激活区域在fMRI语言任务中的功能作用。这些激活的区域包括语言区域，负运动区域，辅助运动区域（SMA）和非功能区域。

结论

fMRI语言映射的激活区域包括与语言相关的区域，负运动区域和SMA。这些发现表明语言和高级运动网络参与言语表达。