Interactions between language and motricity have been a topic of interest in brain development as well as in pathological models. The role of the motor system in language has been investigated through neuroimaging and non-invasive brain stimulation methods. However, little is known about the neural basis that might be involved in such interactions. Meanwhile, brain direct electrostimulations (DES) have provided essential knowledges about the connectomic organization of both motor and language systems. We propose here to review the literature about DES from the outlook of interactions between language and motricity and to investigate common cortico-subcortical structures shared by both networks. Then we will report an experimental study about the spatial distribution of DES eliciting simultaneous speech and contralateral upper limb negative motor response in a series of 100 patients operated on under awake condition for a low-grade glioma. From the probabilistic map obtained, a structural connectivity analysis was performed to reveal the cortico-subcortical networks involved in language and motricity interactions. The embodiment suggested by these results takes place in parallel and distributed bilateral fronto-temporo-parietal networks rather than in a single and somatopically well defined organization as previously suggested.

中文翻译：

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对从外科手术中直接电刺激获得的介导运动/语言相互作用的神经基础的新见解。

语言和运动能力之间的相互作用一直是大脑发育以及病理模型中关注的话题。通过神经影像学和非侵入性脑刺激方法，研究了运动系统在语言中的作用。但是，对于这种相互作用可能涉及的神经基础知之甚少。同时，大脑直接电刺激（DES）提供了有关运动系统和语言系统的连接体组织的基本知识。我们在这里建议从语言和动力之间的相互作用的角度回顾有关DES的文献，并研究两个网络共享的常见皮质-皮层下结构。然后，我们将报告一项有关DES的空间分布的实验研究，该研究在一系列清醒条件下对低级别神经胶质瘤进行手术的100例患者中，同时引起语音和对侧上肢负运动反应。从获得的概率图，进行了结构连通性分析，以揭示参与语言和移动性相互作用的皮质-皮层下网络。这些结果表明的实施方案发生在平行且分布的双边额颞顶网络中，而不是如先前所提出的在单个且在体位上定义良好的组织中。进行了结构连通性分析，以揭示参与语言和动力相互作用的皮质-皮质下网络。这些结果表明的实施方案发生在平行且分布的双边额颞顶网络中，而不是如先前所提出的在单个且在体位上定义良好的组织中。进行了结构连通性分析，以揭示参与语言和动力相互作用的皮质-皮质下网络。这些结果表明的实施方案发生在平行且分布的双边额颞顶网络中，而不是如先前所提出的在单个且在体位上定义良好的组织中。