Abstract

A method of synthesis of organic mono-, di-, and polysulfides based on electrochemical reactions of unsubstituted and alkyl–substituted cycloalkanes C₅–C₈ with di(n-butyl)disulfide (di(tert-butyl)disulfide) and hydrogen sulfide is developed. Three–component electrosynthesis is carried out in methylene chloride under atmospheric pressure, at the room temperature under the conditions of anodic H₂S activation to a cation radical fragmented to a proton and a thiyl radical. The suggested approach with application of oxidative conversion initiation allows obtaining asymmetric mono-, disulfides and symmetric disulfides. The yield of biologically active organic sulfur derivatives depends on the electrosynthesis duration, structure of isomeric dibutyl sulfides, alicycle size and saturation degree.

中文翻译：

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基于C 5 -C 8环烷烃，硫化氢和异构二丁基二硫化物的一硫化物和二硫化物的电合成

摘要

一种基于未取代和烷基取代的环烷烃C ₅ -C ₈与二（正丁基）二硫化物（二（叔丁基）二硫化物）的电化学反应的有机一，二和多硫化物的合成方法被开发。三组分电合成是在大气压下，在室温，阳极H ₂的条件下于二氯甲烷中进行的S活化成阳离子，其分裂成质子和噻吩基。使用氧化转化引发的建议方法允许获得不对称的一，二硫化物和对称的二硫化物。具有生物活性的有机硫衍生物的产率取决于电合成持续时间，异构二丁基硫化物的结构，脂环族化合物的大小和饱和度。