Orthopaedic metallic implant's long-term success strongly depends upon the two main factors: osseointegration and antibacterial character. Bioceramic (hydroxyapatite and hopeite) coatings have been proven effective for getting strong osseointegration and antibacterial character. However, deterioration of bioceramic coatings during the implantation period can adversely affect its overall biological performance. To conquer this issue, this research work recommends an innovative process route of laser rapid manufacturing for depositing bioceramic (hydroxyapatite and hopeite) coatings with metallurgical bonding. Microstructure, phase composition, antibacterial efficacy and bioactivity were evaluated using scanning electron microscopy, X-ray diffraction, fluorescence-activated cell sorting technique and simulated body fluid immersion test. The promising results obtained from these characterizations and testing establish the new process route laser rapid manufacturing as an effective alternative to deposit multifunctional bioceramic (hydroxyapatite and hopeite) coatings on metallic prosthetic-orthopaedic implants.

中文翻译：

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通过激光快速制造在SS254上的多功能羟基磷灰石和希望石涂层，以改善骨整合和抗菌特性：一项对比研究。

骨科金属植入物的长期成功在很大程度上取决于两个主要因素：骨整合和抗菌特性。生物陶瓷（羟基磷灰石和希望石）涂层已被证明可有效实现强大的骨整合和抗菌特性。然而，在植入期间生物陶瓷涂层的变质会不利地影响其整体生物学性能。为了解决这个问题，这项研究工作提出了一种创新的激光快速制造工艺路线，该工艺路线用于通过冶金结合来沉积生物陶瓷（羟基磷灰石和希望石）涂层。使用扫描电子显微镜，X射线衍射，荧光激活细胞分选技术和模拟体液浸没试验评估了显微结构，相组成，抗菌功效和生物活性。