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Reducing visible aerosol generation during phacoemulsification in the era of Covid-19
medRxiv - Ophthalmology Pub Date : 2020-05-18 , DOI: 10.1101/2020.05.14.20102301
Kieren Darcy , Omar Elhaddad , Asaf Achiron , Johannes Keller , Duncan Leadbetter , Derek Tole , Sidath E Liyanage

Objective: To assess potential methods of reducing visible aerosol generation during clear corneal phacoemulsification surgery in the era of Covid-19. Methods: Aerosol generation during phacoemulsification was assessed using a model comprising a human cadaveric corneoscleral rim mounted on an artificial anterior chamber. Typical phacoemulsification settings were used and visible aerosol production was recorded using high speed 4K camera. Aerosolisation was evaluated under various experimental settings: Two different phacoemulsification tip sizes (2.2mm, 2.75mm), varying levels of corneal moisture, the use of suction and blowing air in the surgical field, the use of hydroxypropyl methylcellulose (HPMC) coating of the cornea with a static and moving tip. Results: This model demonstrates visible aerosol generation during phacoemulsification with a 2.75mm phacoemulsification tip. No visible aerosol was noted with a 2.2mm tip. The presence of visible aerosol is unrelated to corneal wetting. Suction in close proximity to the aerosol plume did not impact on its dispersion. Blowing air redirected the aerosol plume towards the ocular surface. Visible aerosol production was abolished when HPMC was used to coat the cornea. This effect lasted for an average of 67±8 seconds in the static model. Visible aerosol generation was discerned during movement of the 2.2mm tip towards the corneal wound. Conclusions: We demonstrate visible aerosol production in the setting of a model of a clear cornea phacoemulsification. Visible aerosol can be reduced using a 2.2mm phacoemulsification tip and reapplying HPMC every minute during phacoemulsification.

中文翻译:

减少Covid-19时代超声乳化期间可见的气溶胶生成

目的:评估在Covid-19时代,在透明角膜超声乳化手术中减少可见气溶胶生成的潜在方法。方法:使用包括安装在人工前房上的人尸体角膜巩膜缘的模型评估超声乳化术期间气雾的产生。使用典型的超声乳化设置,并使用高速4K摄像机记录可见的气溶胶产量。在各种实验设置下对雾化进行了评估:两种不同的超声乳化吸头尺寸(2.2mm,2.75mm),角膜水分水平不同,在外科手术领域中使用抽吸和吹气,在手术室中使用羟丙基甲基纤维素(HPMC)涂层角膜的尖端动静。结果:该模型演示了在超声乳化术中使用2时可见的气溶胶生成。75毫米超声乳化针头。尖端为2.2mm,未发现可见的气溶胶。可见气溶胶的存在与角膜浸润无关。靠近气溶胶羽流的吸气不会影响其散布。吹气将气雾流重新导向眼表。当使用HPMC覆盖角膜时,消除了可见的气溶胶产生。在静态模型中,该效果平均持续67±8秒。在2.2mm尖端向角膜伤口移动的过程中观察到可见的气溶胶生成。结论:在透明角膜超声乳化模型的设置中,我们证明了可见的气溶胶产生。可使用2.2毫米超声乳化针头并在超声乳化过程中每分钟重新应用HPMC来减少可见的气溶胶。尖端为2.2mm,未发现可见的气溶胶。可见气溶胶的存在与角膜浸润无关。靠近气溶胶羽流的吸气不会影响其散布。吹气将气雾流重新导向眼表。当使用HPMC覆盖角膜时,消除了可见的气溶胶产生。在静态模型中,该效果平均持续67±8秒。在2.2mm尖端向角膜伤口移动期间,可见到气溶胶的产生。结论:在透明角膜超声乳化模型的设置中,我们证明了可见的气溶胶产生。可使用2.2毫米超声乳化针头并在超声乳化过程中每分钟重新应用HPMC来减少可见的气溶胶。尖端为2.2mm,未发现可见的气溶胶。可见气溶胶的存在与角膜浸润无关。靠近气溶胶羽流的吸气不会影响其散布。吹气将气雾流重新导向眼表。当使用HPMC覆盖角膜时,消除了可见的气溶胶产生。在静态模型中,该效果平均持续67±8秒。在2.2mm尖端向角膜伤口移动期间,可见到气溶胶的产生。结论:在透明角膜超声乳化模型的设置中,我们证明了可见的气溶胶产生。可使用2.2毫米超声乳化针头并在超声乳化过程中每分钟重新应用HPMC来减少可见的气溶胶。靠近气溶胶羽流的吸气不会影响其散布。吹气将气雾流重新导向眼表。当使用HPMC覆盖角膜时,消除了可见的气溶胶产生。在静态模型中,该效果平均持续67±8秒。在2.2mm尖端向角膜伤口移动期间,可见到气溶胶的产生。结论:在透明角膜超声乳化模型的设置中,我们证明了可见的气溶胶产生。可使用2.2毫米超声乳化针头并在超声乳化过程中每分钟重新应用HPMC来减少可见的气溶胶。靠近气溶胶羽流的吸气不会影响其散布。吹气将气雾流重新导向眼表。当使用HPMC覆盖角膜时,消除了可见的气溶胶产生。在静态模型中,该效果平均持续67±8秒。在2.2mm尖端向角膜伤口移动期间,可见到气溶胶的产生。结论:在透明角膜超声乳化模型的设置中,我们证明了可见的气溶胶产生。可以使用2.2毫米超声乳化吸头减少可见的气溶胶,并在超声乳化期间每分钟重新应用HPMC。当使用HPMC覆盖角膜时,消除了可见的气溶胶产生。在静态模型中,该效果平均持续67±8秒。在2.2mm尖端向角膜伤口移动期间,可见到气溶胶的产生。结论:在透明角膜超声乳化模型的设置中,我们证明了可见的气溶胶产生。可使用2.2毫米超声乳化针头并在超声乳化过程中每分钟重新应用HPMC来减少可见的气溶胶。当使用HPMC覆盖角膜时,消除了可见的气溶胶产生。在静态模型中,该效果平均持续67±8秒。在2.2mm尖端向角膜伤口移动期间,可见到气溶胶的产生。结论:在透明角膜超声乳化模型的设置中,我们证明了可见的气溶胶产生。可以使用2.2毫米超声乳化吸头减少可见的气溶胶,并在超声乳化期间每分钟重新应用HPMC。
更新日期:2020-05-18
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