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Galuteolin, identified in the extract of thymus quinquecostatus flowers, is involved in inhibiting melanin biosynthesis in B16/F10 melanoma cells
Natural Product Research ( IF 1.9 ) Pub Date : 2020-05-18 , DOI: 10.1080/14786419.2020.1768091
Mi-Hee Kim 1 , Bora Kwon 1 , Kwang-Sang Kim 2 , Min-Sook Kim 2 , Min-Ji Kim 2 , Hwa-Jin Kim 2 , Da-In Choi 2 , Miyeon Park 2 , Moosung Kim 3 , Min-Kyu Shin 3 , Seung-Il Jeong 1 , Kang-Yeol Yu 1 , Jiyoung Kim 1
Affiliation  

Abstract

To enhance the skin whitening effect, tyrosinase activity and melanin biosynthesis needs to be suppressed in the skin. To achieve this goal, we examined the extract of Thymus quinquecostatus flowers, and identified a functional ingredient, galuteolin. Galuteolin effectively inhibited melanin biosynthesis in B16/F10 cells, partially suppressing tyrosinase activity. Therefore, this study suggests that galuteolin can be used as a cosmetic ingredient for skin whitening.



中文翻译:

Galuteolin,在胸腺 quinquecostus 花提取物中鉴定,参与抑制 B16/F10 黑色素瘤细胞中黑色素的生物合成

摘要

为了增强皮肤美白效果,需要抑制皮肤中的酪氨酸酶活性和黑色素生物合成。为了实现这一目标,我们检查了百里香花的提取物,并确定了一种功能成分,galuteolin。Galuteolin 有效抑制 B16/F10 细胞中黑色素的生物合成,部分抑制酪氨酸酶活性。因此,这项研究表明,galuteolin 可以用作美白皮肤的化妆品成分。

更新日期:2020-05-18
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