ABSTRACT Objective The aim of the study was to compare the complication of Antihypertensive drug; in pregnant women with chronic hypertension. Method This retrospective cohort study was performed on 300 pregnant women with chronic hypertension. Results: a relative risk of preeclampsia among methyldopa group was 3.45 times higher than the metoprolol, the relative risk of preterm labor was not significantly between methyldopa and metoprolol group, LBW, and IUGR in methyldopa and amlodipine groups . Conclusion Methyldopa and amlodipine are associated with the least side effects in pregnant women treated for chronic hypertension.the incidence of preeclampsia was greater in methyldopa group.

中文翻译：

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甲基多巴、氨氯地平、美托洛尔对慢性高血压孕妇副作用的比较

摘要 目的比较降压药的并发症；在患有慢性高血压的孕妇中。方法 这项回顾性队列研究对 300 名患有慢性高血压的孕妇进行。结果：甲基多巴组发生先兆子痫的相对风险是美托洛尔组的3.45倍，甲基多巴组与美托洛尔组的早产相对风险、甲基多巴组和氨氯地平组的LBW和IUGR的相对风险不显着。结论 甲基多巴和氨氯地平在接受慢性高血压治疗的孕妇中副作用最小，甲基多巴组先兆子痫的发生率更高。