Eurycoma longifolia Jack (Simaroubaceae ) is commonly distributed in the Southeast Asia and Indo China, which has been shown to possess antianxiety, antibacterial, anticancer, antifungal, anti‐inflammatory, antimalarial and antioxidant biological activities. 14,15β‐dihydroxyklaineanone is a diterpene isolated from E. longifolia Jack , which is cytotoxic against human lung cancer and human breast cancer cell lines. However, the effects and underlying mechanisms of 14,15β‐dihydroxyklaineanone on hepatocellular carcinoma remain unknown.

中文翻译：

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14,15-dihydroxyklaineanone通过p38MAPK途径抑制HepG2细胞的增殖和迁移。

长叶杜鹃（Simaroubaceae）常见于东南亚和印度支那，已被证明具有抗焦虑，抗菌，抗癌，抗真菌，抗炎，抗疟疾和抗氧化的生物活性。14,15β-dihydroxyklaineanone是从E.longifolia Jack分离的二萜，对人肺癌和人乳腺癌细胞系具有细胞毒性。然而，尚不清楚14,15β-二羟基可乐酮对肝细胞癌的影响及其潜在机制。