Interleukin‐7 (IL‐7) is the most important cytokine for T‐cell homeostasis. IL‐7 signals through the IL‐7 receptor (IL‐7R) which is composed of an alpha chain (IL‐7Rα), also called CD127 and a common gamma chain. T lymphocytes, especially T helper type 2, play a crucial role in the pathobiology of allergic asthma.

中文翻译：

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通过抗 CD127 单克隆抗体靶向白细胞介素 7 受体 α 可改善小鼠的过敏性气道炎症

白细胞介素-7 (IL-7) 是 T 细胞稳态最重要的细胞因子。IL-7 通过 IL-7 受体 (IL-7R) 发出信号，IL-7R 由 α 链 (IL-7Rα)，也称为 CD127 和常见的 γ 链组成。T 淋巴细胞，尤其是 T 辅助细胞类型 2，在过敏性哮喘的病理生物学中起关键作用。