We show that polarization‐sensitive optical coherence tomography angiography (PS‐OCTA) based on full Jones matrix assessment of speckle decorrelation offers improved contrast and depth of vessel imaging over conventional OCTA. We determine how best to combine the individual Jones matrix elements and compare the resulting image quality to that of a conventional OCT scanner by co‐locating and imaging the same skin locations with closely matched scanning setups. Vessel projection images from finger and forearm skin demonstrate the benefits of Jones matrix‐based PS‐OCTA. Our study provides a promising starting point and a useful reference for future pre‐clinical and clinical applications of Jones matrix‐based PS‐OCTA.

中文翻译：

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基于琼斯矩阵的散斑去相关血管造影，使用偏振敏感光学相干断层扫描。

我们展示了基于散斑去相关的完整琼斯矩阵评估的偏振敏感光学相干断层扫描血管造影（PS-OCTA）与常规OCTA相比提供了改善的对比度和深度的血管成像。我们确定如何最好地组合各个Jones矩阵元素，并通过使用紧密匹配的扫描设置对同一皮肤位置进行共置位和成像，从而将所得图像质量与传统OCT扫描仪的图像质量进行比较。手指和前臂皮肤的血管投影图像证明了基于Jones矩阵的PS-OCTA的优势。我们的研究为基于琼斯矩阵的PS-OCTA的未来临床前和临床应用提供了有希望的起点和有用的参考。