Cortical Motor Areas Show Different Reorganizational Changes in Adult Patients with Brachial Plexus Birth Injury (BPBI),International Journal of Developmental Neuroscience

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Cortical Motor Areas Show Different Reorganizational Changes in Adult Patients with Brachial Plexus Birth Injury (BPBI)
International Journal of Developmental Neuroscience ( IF 1.7 ) Pub Date : 2020-06-02 , DOI: 10.1002/jdn.10037
Zeynep Tuna ₁ , Deran Oskay ₁ , Oktay Algin ₂ , Orhan Murat Koçak ₃

Affiliation

INTRODUCTION Brachial plexus birth injury (BPBI) may cause permanent disability. It is recently thought to result from the (mal)adaptive reorganizational central nervous system problems. METHODS In this study, adult patients with BPBI and age-matched healthy controls were compared for the cortical activity during action observation by functional magnetic resonance imaging (fMRI). RESULTS The cortical activity in patients was significantly weaker than in the control group (p <0, 05). Areas of difference were middle temporal gyrus, premotor area and inferior parietal lobule. The signal change in these areas was significantly lower in the patient group (p<0, 05). CONCLUSIONS This study showed that the cortical activity in the associative motor regions was weaker in the patients while no primary region showed any difference. The results were concluded that there is a diversity in the neuroplastic changes between primary and associative motor areas. Clinically, neurorehabilitative interventions should be planned based on this diversity.

中文翻译：

臂丛神经出生损伤 (BPBI) 成年患者的皮质运动区表现出不同的重组变化

简介臂丛神经产伤 (BPBI) 可能会导致永久性残疾。最近认为这是由（不良）适应性重组中枢神经系统问题引起的。方法在本研究中，通过功能磁共振成像 (fMRI) 观察动作时，比较 BPBI 成年患者和年龄匹配的健康对照者的皮质活动。结果患者的皮质活动明显弱于对照组 (p <0, 05)。差异区域为颞中回、运动前区和顶下小叶。患者组中这些区域的信号变化显着较低 (p<0, 05)。结论本研究表明，患者联想运动区的皮质活动较弱，但主要区域没有表现出任何差异。结果得出的结论是，初级运动区和联想运动区之间的神经可塑性变化存在多样性。临床上，神经康复干预措施应根据这种多样性进行规划。

更新日期：2020-06-02

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