Idiopathic normal pressure hydrocephalus (iNPH) is a clinical entity without established pathological hallmarks. Previous autopsy studies reported that patients with an antemortem diagnosis of iNPH had a different postmortem diagnosis, commonly progressive supranuclear palsy (PSP). Disproportionately enlarged subarachnoid space hydrocephalus (DESH) has been reported as a characteristic feature of iNPH on magnetic resonance imaging (MRI). In addition, periventricular white matter hyperintensities (PVHs) are noted in most patients with iNPH; these PVHs are supposed to reflect transependymal movement of ventricular cerebrospinal fluid. It is hypothesized that PSP develops more iNPH‐like MRI features than other neurodegenerative disorders.

中文翻译：

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进行性核上性麻痹通常会出现特发性正常压力脑积水样磁共振成像特征。

特发性正常压力脑积水 (iNPH) 是一种没有既定病理特征的临床实体。先前的尸检研究报告称，死前诊断为 iNPH 的患者有不同的死后诊断，通常为进行性核上性麻痹 (PSP)。不成比例增大的蛛网膜下腔积水 (DESH) 已被报道为核磁共振成像 (MRI) 上 iNPH 的特征。此外，在大多数 iNPH 患者中注意到脑室周围白质高信号 (PVH)；这些 PVH 应该反映心室脑脊液的经室管膜运动。据推测，与其他神经退行性疾病相比，PSP 会出现更多类似 iNPH 的 MRI 特征。