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Low-molecular weight peptides isolated from seahorse (Hippocampus abdominalis) improve vasodilation via inhibition of angiotensin-converting enzyme in vivo and in vitro
Process Biochemistry ( IF 3.7 ) Pub Date : 2020-08-01 , DOI: 10.1016/j.procbio.2020.04.016
Jun-Geon Je , Hyun-Soo Kim , Hyo-Geun Lee , Jae-Young Oh , Yu An Lu , Lei Wang , Sum Rho , You-Jin Jeon

Abstract According to relevant literature, the consumption of seahorses has been used to increase male functions by improving blood flow and decreasing blood pressure. Thus, it was theorized that seahorses may also be effective against hypertension. Herein, vasodilation caused via the inhibitory effect of angiotensin-converting enzymes (ACEs) in peptides was elucidated by studying the seahorses (Hippocampus abdominalis) farmed at Jeju in South Korea. Hydrolysate was prepared using the Protamex (SHP) enzyme. The ultrafiltration system was adopted to separate certain fractions from SHP according to different molecular weights (SHP-I, MW > 10 kDa; SHP-II, MW = 5−10 kDa; SHP-III, MW

中文翻译:

从海马(海马腹肌)中分离的低分子量肽通过在体内和体外抑制血管紧张素转换酶来改善血管舒张

摘要 根据相关文献,食用海马已被用于通过改善血液流动和降低血压来增强男性功能。因此,理论上海马也可能对高血压有效。在本文中,通过研究韩国济州岛养殖的海马(Hippocampus腹部),阐明了由肽中血管紧张素转换酶(ACE)的抑制作用引起的血管舒张。使用 Protamex (SHP) 酶制备水解产物。采用超滤系统从SHP中分离出不同分子量的部分(SHP-I, MW > 10 kDa; SHP-II, MW = 5−10 kDa; SHP-III, MW
更新日期:2020-08-01
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