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Longitudinal correlation between neurofilament light chain and UMSARS in Multiple System Atrophy.
Clinical Neurology and Neurosurgery ( IF 1.8 ) Pub Date : 2020-05-16 , DOI: 10.1016/j.clineuro.2020.105924
Carla Palleis 1 , Estrella Morenas-Rodriguez 2 , Francisco Jesús Martínez Murcia 3 , Armin Giese 4 , Brigitte Nuscher 5 , Christian Haass 2 , Günter Höglinger 6 , Kai Bötzel 7 , Johannes Levin 8
Affiliation  

In this case of a patient with Multiple System Atrophy of the cerebellar type, we show how plasma levels of Neurofilament light evolve over time in correlation to the clinical progression using the Unified MSA Rating Scale. We discuss that Neurofilament light is a potential biomarker to track disease progression in Multiple System Atrophy.



中文翻译:

多系统萎缩中神经丝轻链和UMSARS之间的纵向相关性。

在小脑型多系统萎缩患者的情况下,我们使用统一MSA评分量表显示了神经丝光的血浆水平如何随时间变化与临床进展相关。我们讨论神经丝灯是潜在的生物标志物,以跟踪多系统萎缩症的疾病进展。

更新日期:2020-05-16
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