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Exploring neutron capture therapy with 33S and 10B.
Applied Radiation and Isotopes ( IF 1.6 ) Pub Date : 2020-05-16 , DOI: 10.1016/j.apradiso.2020.109220
I López-Casas 1 , J Praena 1 , F Arias de Saavedra 1 , M Sabaté-Gilarte 2 , I Porras 1
Affiliation  

The 33S(n,α)30Si reaction was proposed as cooperative neutron capturer to 10B(n,α)7Li in Neutron Capture Therapy (NCT). At that moment, the available 33S(n,α)30Si cross-section data were scarce and discrepant in key energy ranges for its use in NCT. Since then, three experiments have been carried out at n_TOF facility at CERN and at Institut Laue-Langevin. These new data are used for the calculation of the dose rate on ICRU-4 tissue by using kerma factors, a simplified model of tissue and a 13.45 keV neutron beam, energy of the most important 33S(n,α)30Si resonance. A significant enhancement of the dose rate due to the presence of 33S is shown. In spite of the limitations, the cooperative action of 33S and 10B is an interesting possibility to be studied for accelerator-based neutron sources with non-moderated neutrons.



中文翻译:

探索 33S 和 10B 的中子俘获疗法。

33 S(N,α)30的Si反应提议作为合作中子俘获到10 B(N,α)7栗在中子俘获治疗(NCT)。在那一刻,可用的33 S(n,α) 30 Si 横截面数据稀缺,并且在用于 NCT 的关键能量范围内存在差异。从那时起,在欧洲核子研究中心的 n_TOF 设施和劳厄-朗之万研究所进行了三项实验。这些新数据用于计算 ICRU-4 组织上的剂量率,方法是使用比释动系数、组织的简化模型和 13.45 keV 中子束、最重要的33 S(n,α) 30 Si 共振能量。由于存在的剂量率显着提高显示了 33 S。尽管存在局限性,但33 S 和10 B的协同作用对于基于加速器的中子源与非慢化中子进行研究是一种有趣的可能性。

更新日期:2020-05-16
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