Animal Reproduction Science ( IF 2.2 ) Pub Date : 2020-05-17 , DOI: 10.1016/j.anireprosci.2020.106503 Janice L Bailey 1 , Mathieu Dalvai 1 , Maryse Lessard 1 , Pauline M Herst 1 , Phanie L Charest 1 , P Navarro 1
In light of the relatively ignored role of paternal influences on offspring development and increasing societal concerns regarding possible health consequences of chemical exposures, our team has addressed the overall hypothesis that environmentally-relevant levels of contaminants have long-lasting effects that are transmitted through the paternal lineage. This review focuses on our research examining the impact of developmental exposure to toxicants and nutrients on the phenotype and epigenome of the male and of his subsequent generations. This report is intended to encourage animal andrologists as well as the domestic animal production industry to increase their consideration of the sire’s environment in the context of agricultural productivity.
中文翻译:
超越受精:父系环境如何影响后代。
鉴于父亲对后代发育的影响相对被忽视,以及越来越多的社会对化学品暴露可能带来的健康后果的担忧,我们的团队已经解决了总体假设,即与环境相关的污染物水平具有通过父系传播的长期影响。血统。本综述侧重于我们的研究,研究发育暴露于毒物和营养物质对男性及其后代的表型和表观基因组的影响。本报告旨在鼓励动物男学家以及家畜生产行业在农业生产力的背景下增加对公牛环境的考虑。