COVID-19 virus may have neuroinvasive potential and cause neurological complications: a perspective review.,Journal of Neurovirology

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COVID-19 virus may have neuroinvasive potential and cause neurological complications: a perspective review.
Journal of Neurovirology ( IF 2.3 ) Pub Date : 2020-05-16 , DOI: 10.1007/s13365-020-00851-2
Ali Sepehrinezhad _{1,

2} , Ali Shahbazi _{1,

3} , Sajad Sahab Negah _{2,

4,

5}

Affiliation

Coronavirus disease 2019 (COVID-19) was reported at the end of 2019 in China for the first time and has rapidly spread throughout the world as a pandemic. Since COVID-19 causes mild to severe acute respiratory syndrome, most studies in this field have only focused on different aspects of pathogenesis in the respiratory system. However, evidence suggests that COVID-19 may affect the central nervous system (CNS). Given the outbreak of COVID-19, it seems necessary to perform investigations on the possible neurological complications in patients who suffered from COVID-19. Here, we reviewed the evidence of the neuroinvasive potential of coronaviruses and discussed the possible pathogenic processes in CNS infection by COVID-19 to provide a precise insight for future studies.

更新日期：2020-05-16

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