Microneedle patch based on dissolving, detachable microneedle technology for improved skin quality - Part 1: ex vivo safety evaluation.,International Journal of Cosmetic Science

当前位置： X-MOL 学术 › Int. J. Cosmet. Sci. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Microneedle patch based on dissolving, detachable microneedle technology for improved skin quality - Part 1: ex vivo safety evaluation.
International Journal of Cosmetic Science ( IF 2.7 ) Pub Date : 2020-07-05 , DOI: 10.1111/ics.12627
V Zvezdin ₁ , L Peno-Mazzarino ₂ , N Radionov ₂ , T Kasatkina ₃ , I Kasatkin ₃

Affiliation

The aim of the paper presented herein is the description and safety evaluation of the process of dissolution of an 86‐microneedle patch composed of hyaluronic acid, when applied topically to human abdominal skin explants. Such explants were chosen to replace the inability of obtaining periorbital skin. In order to evaluate penetration and dissolution of the microneedles, we employed histochemical methods and a fluorescent dye FITC (fluorescein isothiocyanate).

中文翻译：

基于可溶解、可拆卸微针技术改善皮肤质量的微针贴片 - 第 1 部分：离体安全性评估。

本文的目的是描述和安全性评估由透明质酸组成的 86 微针贴片在局部应用于人体腹部皮肤外植体时的溶解过程。选择这样的外植体来代替无法获得眶周皮肤的情况。为了评估微针的穿透和溶解，我们采用了组织化学方法和荧光染料 FITC（异硫氰酸荧光素）。

更新日期：2020-07-05

点击分享查看原文

点击收藏

阅读更多本刊最新论文本刊介绍/投稿指南11