COVID-19 pandemic caused by SARS-CoV-2, continues to manifest with severe acute respiratory syndrome among the adults, however, it offers a convincing indication of less severity and fatality in pediatric age group (0–18 years). The current trend suggests that children may get infected but are less symptomatic with less fatality, which is concordant to earlier epidemic outbreaks of SARS-CoV and MERS-CoV, in 2002 and 2012, respectively. According to the available data, children appear to be at lower risk for COVID-19, as adults constitute for maximum number of the confirmed cases (308,592) and deaths (13,069) as on 22nd March (https://www.worldometers.info/coronavirus). However, rapid publications and information of the adult patients with COVID-19 is in progress and published, on the contrary, almost no comprehensive data or discussion about the COVID-19 in children is available. Therefore, in this review, we outline the epidemiology, clinical symptoms, diagnosis, treatment, prevention, possible immune response and role of thymus in children to combat the COVID-19 outbreak.

由 SARS-CoV-2 引起的 COVID-19 大流行在成人中继续表现为严重急性呼吸系统综合症，但它提供了令人信服的迹象，表明儿科年龄组（0-18 岁）的严重程度和死亡率较低。目前的趋势表明，儿童可能会被感染，但症状较轻，死亡率也较低，这与 2002 年和 2012 年分别爆发的 SARS-CoV 和 MERS-CoV 的早期流行病一致。根据现有数据，截至 3 月 22 日，儿童感染 COVID-19 的风险似乎较低，因为成人占确诊病例数 (308,592 例) 和死亡人数 (13,069 例) (https://www.worldometers.info /冠状病毒）。然而，成人 COVID-19 患者的快速出版物和信息正在进行中并已发表，相反，几乎没有关于儿童 C​​OVID-19 的全面数据或讨论。因此，在这篇综述中，我们概述了儿童的流行病学、临床症状、诊断、治疗、预防、可能的免疫反应以及胸腺在对抗 COVID-19 爆发中的作用。