Four unreported carbazole alkaloids named as claulansines U – W (1, 2, 4), (–) -(2′R)-claulamine A (3b) and one known analogue, claulamine A (3a) were obtained from the stems of Clausena lansium. Their structures were demonstrated by spectroscopic experiments. The absolute configuration of claulansine U (1) was determined by single-crystal X-ray diffraction analysis. Compounds 1 and 2 protected PC12 cells against serum deprivation injury at 10μM — an increase of cell survival rates from 47.4 ± 4.3 % (model) to 67.8 ± 6.6 % and 63.3 ± 8.2 %, respectively. And compound 4 showed significant cytotoxicities to four human cancer cell lines, with IC₅₀ values ranging from 2.16 to 4.94 μM.

命名为claulansines四个未报告咔唑生物碱ù - W（1，2，4），（ - ） - （2' - [R）-claulamine A（图3b）和一个已知的类似物，claulamine A（图3a获得）从茎黄皮黄皮。通过光谱实验证明了它们的结构。通过单晶X射线衍射分析确定了青草素U（1）的绝对构型。化合物1个2抗血清剥夺损伤保护PC12细胞在10 μM-细胞存活率分别从47.4±4.3％（模型）增加到67.8±6.6％和63.3±8.2％。和化合物4显示出细胞毒性显著至四个人癌细胞系，用IC _50个值范围为2.16至4.94 μ M.