Abstract Nanostructural hybrid organic-inorganic metal halide perovskites offer a wide range of potential applications including photovoltaics, solar cells, and light emitting diodes. Up to now the surface stabilizing ligands were used solely to obtain the optimal properties of nanoparticles in terms of dimensionality and stability, however their possible additional functionality was rarely considered. In the present work, hybrid lead bromide perovskite nanoparticles (PNP) were prepared using a unique approach where a peptide nucleic acid is used as a surface ligand. Methylammonium lead bromide perovskite colloidal nanoparticles stabilized by thymine-based peptide nucleic acid monomer (PNA-M) and relevant trimer (PNA-T) were prepared exhibiting the size below 10 nm. Perovskite structure and crystallinity were verified by X-ray powder diffraction spectroscopy and high resolution transmission electron microscopy. PNP-PNA-M and PNP-PNA-T colloidal dispersions in chloroform and toluene possessed green-blue fluorescence, while Fourier-transform infrared spectroscopy (FT-IR) and quantum chemical calculations showed that the PNA coordinates to the PNP surface through the primary amine group. Additionally, the sensing ability of the PNA ligand for adenine nucleic acid was demonstrated by photoluminescence quenching via charge transfer. Furthermore, PNP thin films were effectively produced by the centrifugal casting. We envision that combining the unique, tailored structure of peptide nucleic acids and the prospective optical features of lead halide perovskite nanoparticles could expand the field of applications of such hybrids exploiting analogous ligand chemistry.

中文翻译：

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用于核酸传感的肽核酸稳定钙钛矿纳米颗粒

摘要 纳米结构杂化有机-无机金属卤化物钙钛矿提供了广泛的潜在应用，包括光伏、太阳能电池和发光二极管。到目前为止，表面稳定配体仅用于获得纳米粒子在维度和稳定性方面的最佳性能，但很少考虑它们可能的附加功能。在目前的工作中，使用一种独特的方法制备了混合溴化铅钙钛矿纳米粒子 (PNP)，其中肽核酸用作表面配体。制备了由基于胸腺嘧啶的肽核酸单体 (PNA-M) 和相关三聚体 (PNA-T) 稳定的甲基铵溴化铅钙钛矿胶体纳米粒子，其尺寸小于 10 nm。通过 X 射线粉末衍射光谱和高分辨率透射电子显微镜验证了钙钛矿结构和结晶度。氯仿和甲苯中的 PNP-PNA-M 和 PNP-PNA-T 胶体分散体具有绿蓝色荧光，而傅里叶变换红外光谱 (FT-IR) 和量子化学计算表明 PNA 通过初级与 PNP 表面配位。胺基团。此外，通过电荷转移的光致发光猝灭证明了 PNA 配体对腺嘌呤核酸的传感能力。此外，通过离心浇铸有效地生产了 PNP 薄膜。我们设想结合独特的，