Abstract A new set of revised parameters for NRTL activity coefficient model was correlated for the quaternary mixture of acetic acid + isoamyl alcohol + isoamyl acetate + water based on available scientific experimental vapor – liquid, liquid – liquid and vapor – liquid – liquid equilibrium data. The structure of residue curve maps for the non-reactive quaternary mixture presents four binary azeotropes and two ternary azeotropes. No reactive azeotropes were found for the reactive system. The new set of parameters for NRTL activity coefficient model is more consistent with experimental data than current models and their predictions are used to calculate a complete thermodynamic characterization for the reactive and nonreactive fluid phase equilibria. The results can be used in reactive distillation calculations such as process synthesis and conceptual design.

中文翻译：

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反应精馏法生产乙酸异戊酯的液相平衡

摘要 基于现有的科学实验汽-液、液-液和汽-液-液平衡数据，对乙酸+异戊醇+乙酸异戊酯+水的四元混合物建立了一套新的NRTL活度系数模型修正参数。非反应性四元混合物的残留曲线图结构呈现四个二元共沸物和两个三元共沸物。对于反应体系没有发现反应性共沸物。NRTL 活度系数模型的新参数集比当前模型更符合实验数据，并且它们的预测用于计算反应性和非反应性流体相平衡的完整热力学特征。