Abstract Processive phytochemistry and pharmacological investigation of Schefflera leucantha R.Vig. (Araliaceae) led to the isolation of fifteen known compounds: a nucleobase (1), six small aromatic molecules (2–7), three phenylpropanoids (8–10), four lignans (11–14) and a fatty acid derivative (15). Spectroscopic methods were used to establish the structure and configuration of isolates, followed by their unambiguous confirmation with literature data. We report for the first time (to the best of our knowledge), the isolation of β-amino-3-methoxy-4-hydroxybenzene-ethanol (4) from a natural source. Furthermore, compounds 1, 5, 9–15 are being reported from Araliaceae family for the first time, whereas compounds 2, 3, 6–8 from the genus Schefflera for the first time. The biological screening results show that compounds 9 and 10 induce a moderate inhibitory effect on aldose reductase, while compounds 3, 5, and 8 display significantly high neuroprotective activities.

中文翻译：

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来自 Schefflera leucantha R.Vig 的化学成分。(五加科)

摘要 Schefflera leucantha R.Vig 的进行性植物化学和药理研究。（五加科）分离出 15 种已知化合物：一个核碱基 (1)、六个芳香族小分子 (2-7)、三个苯丙烷 (8-10)、四个木脂素 (11-14) 和一个脂肪酸衍生物 (15 ）。光谱方法用于建立分离物的结构和构型，然后用文献数据对其进行明确确认。我们首次报告（据我们所知）从天然来源中分离出 β-amino-3-methoxy-4-hydroxybenzo-ethanol (4)。此外，化合物 1、5、9-15 是首次报道来自五加科的化合物，而化合物 2、3、6-8 则来自鹅掌楸属首次报道。