Anthracycline is a mainstay in treatment of many cancers including lymphoma and breast cancer among many others. However, anthracycline treatment can be cardiotoxic. Although anthracycline-induced cardiotoxicity is dose dependent, it can also occur early at the onset of treatment and even up to several years following completion of treatment. This review article focuses on the understanding of mechanisms of anthracycline-induced cardiotoxicity, the treatments, and recommended follow-up and preventive approaches.

中文翻译：

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蒽环类药物引起的心脏毒性：作用机制、发生率、危险因素、预防和治疗。

蒽环类药物是治疗多种癌症的中流砥柱，包括淋巴瘤和乳腺癌等。然而，蒽环类药物治疗可能具有心脏毒性。虽然蒽环类药物引起的心脏毒性是剂量依赖性的，但它也可能在治疗开始时发生，甚至在治疗完成后的几年内发生。这篇综述文章的重点是对蒽环类药物引起的心脏毒性机制的理解、治疗方法以及推荐的随访和预防方法。