We aimed to develop a molecularly imprinted polymeric systems with using penicillin G as a template molecule for removal of the antibiotic residues from environmental samples. Firstly, Pen-G-imprinted poly (2-hydroxyethyl methacrylate-N-methacryloyl-l-alanine) [p(HEMA-MAAL)] nanopolymers were synthesized by surfactant-free emulsion polymerization method. Then, template molecule (Pen-G) was extracted from nanopolymers. Synthesized nanopolymers were characterized by different methods such as Fourier-transform infrared spectroscopy (FTIR), elemental and zeta-size analysis, scanning electron microscope (SEM), and surface area calculations. Nanopolymers have 60.38 nm average size and 1034.22 m²/g specific surface area. System parameters on Pen-G adsorption onto Pen-G imprint nanopolymers were investigated at different conditions. The specific adsorption value (Q_max) of molecularly impirinted p(HEMA-MAAL) nanopolymers was found 71.91 g/g for Pen-G in 5 mg/mL Pen-G initial concentration. Pen-G adsorption of molecularly imprinted nanopolymers was 15 times more than non-imprinted polymer. It is shown that obtained p(HEMA-MAAL) nanopolymer was a reuseable product which protected its adsorption capacity of 98.9% after 5th adsorption-desorption cycle. In conclusion, we suggest a method to develop a nanostructure, selective, low-cost molecularly imprinted polymeric systems with using penicillin G as a template molecule for removal of the antibiotic residues.

中文翻译：

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使用聚合物分子印迹纳米材料去除青霉素G的模型研究。

我们旨在开发一种以青霉素G为模板分子的分子印迹聚合物系统，以从环境样品中去除抗生素残留物。首先，通过无表面活性剂乳液聚合法合成了Pen-G印迹的聚（甲基丙烯酸2-羟乙酯-N-甲基丙烯酰基-1-丙氨酸）[p（HEMA-MAAL）]纳米聚合物。然后，从纳米聚合物中提取模板分子（Pen-G）。合成的纳米聚合物通过不同的方法进行表征，例如傅立叶变换红外光谱（FTIR），元素和Zeta尺寸分析，扫描电子显微镜（SEM）和表面积计算。纳米聚合物的平均尺寸为60.38 nm，1034.22 m ²/ g比表面积。在不同条件下研究了Pen-G吸附到Pen-G印迹纳米聚合物上的系统参数。发现在5 mg / mL的Pen-G初始浓度下，分子隐含的p（HEMA-MAAL）纳米聚合物的比吸附值（Q _max）对于Pen-G为71.91 g / g。分子印迹纳米聚合物的Pen-G吸附是非印迹聚合物的15倍。结果表明，所获得的p（HEMA-MAAL）纳米聚合物是可重复使用的产品，在第五次吸附-解吸循环后，其吸附能力达到98.9％。总之，我们建议一种方法，以青霉素G为模板分子去除抗生素残留物，从而开发出一种纳米结构，选择性，低成本的分子印迹聚合物系统。