当前位置: X-MOL 学术Allergy Asthma Clin. Immunol. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Quercetin with the potential effect on allergic diseases.
Allergy, Asthma & Clinical Immunology ( IF 2.6 ) Pub Date : 2020-05-14 , DOI: 10.1186/s13223-020-00434-0
Morteza Jafarinia 1 , Mahnaz Sadat Hosseini 1 , Neda Kasiri 1 , Niloofar Fazel 1 , Farshid Fathi 1 , Mazdak Ganjalikhani Hakemi 1 , Nahid Eskandari 1, 2
Affiliation  

Quercetin is a naturally occurring polyphenol flavonoid which is rich in antioxidants. It has anti-allergic functions that are known for inhibiting histamine production and pro-inflammatory mediators. Quercetin can regulate the Th1/Th2 stability, and decrease the antigen-specific IgE antibody releasing by B cells. Quercetin has a main role in anti-inflammatory and immunomodulatory function which makes it proper for the management of different diseases. Allergic diseases are a big concern and have high health care costs. In addition, the use of current therapies such as ß2-agonists and corticosteroids has been limited for long term use due to their numerous side effects. Since the effect of quercetin on allergic diseases has been widely studied, in the current article, we review the effect of quercetin on allergic diseases, such as allergic asthma, allergic rhinitis (AR), and atopic dermatitis (AD).

中文翻译:

槲皮素对过敏性疾病具有潜在的作用。

槲皮素是天然存在的多酚类黄酮,富含抗氧化剂。它具有抗过敏功能,众所周知可以抑制组胺产生和促炎介质。槲皮素可以调节Th1 / Th2稳定性,并减少B细胞释放的抗原特异性IgE抗体。槲皮素在抗炎和免疫调节功能中起主要作用,使其适合治疗各种疾病。过敏性疾病是一个大问题,并且医疗费用很高。另外,由于它们的许多副作用,长期疗法如β2-激动剂和皮质类固醇的使用受到限制。由于槲皮素对过敏性疾病的作用已得到广泛研究,因此在本文中,我们将对槲皮素对过敏性疾病(如过敏性哮喘,
更新日期:2020-05-14
down
wechat
bug